In 2016,Gunasekara, Roshan W.; Zhao, Yan published 《Enhancing binding affinity and selectivity through preorganization and cooperative enhancement of the receptor》.Chemical Communications (Cambridge, United Kingdom) published the findings.Electric Literature of C12H22F6N6OP2 The information in the text is summarized as follows:
When direct host-guest binding interactions are weakened by unfavorable solvent competition, guest-triggered intra-receptor interactions could be used to augment the binding. This strategy of cooperative enhancement, when combined with the principle of preorganization, yielded a strong and selective receptor for binding citrate in water. In the experiment, the researchers used ((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tris(dimethylamino)phosphonium hexafluorophosphate(V)(cas: 56602-33-6Electric Literature of C12H22F6N6OP2)
((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tris(dimethylamino)phosphonium hexafluorophosphate(V)(cas: 56602-33-6) is a peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.Electric Literature of C12H22F6N6OP2
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics