Interesting scientific research on 86404-63-9

After consulting a lot of data, we found that this compound(86404-63-9)Category: triazoles can be used in many types of reactions. And in most cases, this compound has more advantages.

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 86404-63-9, is researched, SMILESS is FC1=CC=C(C(CN2N=CN=C2)=O)C(F)=C1, Molecular C10H7F2N3OJournal, Bioorganic & Medicinal Chemistry Letters called Novel antifungal 2-aryl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol derivatives with high activity against Aspergillus fumigatus, Author is Dickinson, Roger P.; Bell, Andrew S.; Hitchcock, Christopher A.; Narayanaswami, Subramaniyan; Ray, Stephen J.; Richardson, Kenneth; Troke, Peter F., the main research direction is aryltriazolylbutanol preparation fungicide; triazolylbutanol aryl preparation fungicide; voriconazole preparation fungicide.Category: triazoles.

Replacement of one triazole ring of fluconazole with 4-pyridinyl leads to an increase in activity against Aspergillus fumigatus. Introduction of an α-Me group has a marked addnl. beneficial effect. Investigation of pyridinyl and pyrimidinyl analogs resulted in the identification of compound I (UK-109,496, voriconazole) which has excellent potency against a broad range of fungal pathogens including A. fumigatus and Candida krusei.

After consulting a lot of data, we found that this compound(86404-63-9)Category: triazoles can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics