COA of Formula: C30H30N10In 2021 ,《Vitamin B12 Derivatives Suitably Tailored for the Synthesis of Photolabile Conjugates》 was published in Organic Letters. The article was written by Jackowska, Agnieszka; Gryko, Dorota. The article contains the following contents:
Vitamin B12 conjugates are broadly studied in biol. sciences. A method for the preparation of vitamin B12 conjugates that release tethered mols. upon exposure to light, is reported. Herein, we report vitamin B12 derivatives possessing a photolabile linker suitable for conjugation with amines, azides, and alkynes. The potential applications of such conjugates are broad and include the delivery of drugs, labels, and imaging agents to their place of action and spatiotemporal release. The results came from multiple reactions, including the reaction of Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8COA of Formula: C30H30N10)
Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) is a polytriazolylamine ligand which stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.COA of Formula: C30H30N10
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics