Recommanded Product: 3-Nitro-1-tosyl-1H-1,2,4-triazoleOn November 15, 1980 ,《Synthesis of the 3′-terminal decaribonucleoside nonaphosphate of yeast alanine transfer ribonucleic acid》 appeared in Tetrahedron. The author of the article were Jones, S. S.; Rayner, B.; Reese, C. B.; Ubasawa, A.; Ubasawa, M.. The article conveys some information:
The yeast decaribonucleotide UpCpGpUpCpCpApCpCpA was prepared from the 5 nucleosides I (R = 4-N-benzoylcytosin-1-yl, 2-N-benzoylguanin-9-yl), II (R = 6-N-benzoyladenin-9-yl, uracil-1-yl), and III (R = 6-N-benzoyladenin-9-yl) by the phosphotriester method. The use of o-dibromomethylbenzoyl as a protecting group in oligoribonucleotide synthesis is described. The internucleotide linkages were protected by o-chlorophenyl groups, which were readily removed by the N1,N1,N3,N3-tetramethylguanidinium salt of syn-4-nitrobenzaldoxime. The 1st phosphorylation step was carried out by treatment with o-chlorophenylphosphorodi(1,2,4-triazolide) followed by H2O and Et3N. The triazole IV was used as the activating agent in the 2nd phosphorylation step. In the part of experimental materials, we found many familiar compounds, such as 3-Nitro-1-tosyl-1H-1,2,4-triazole(cas: 77451-51-5Recommanded Product: 3-Nitro-1-tosyl-1H-1,2,4-triazole)
3-Nitro-1-tosyl-1H-1,2,4-triazole(cas: 77451-51-5) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties Recommanded Product: 3-Nitro-1-tosyl-1H-1,2,4-triazole
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics