On July 20, 2011, Kuang, Chunxiang; Wang, Xiaokun published a patent.SDS of cas: 5301-96-2 The title of the patent was Method for synthesis of 4-aryl-1H-1,2,3-triazole with 1,1-dibromo-1-alkene. And the patent contained the following:
A process for preparation of 4-aryl-1H-1,2,3-triazole with 1,1-dibromo-2-aryl-1-alkene and azides via cyclization in the presence of catalyst and ligand is disclosed. The claimed 4-aryl-1H-1,2,3-triazole is shown in structure I (Ar = substituted phenyl). The claimed title compound is prepared with 1,1-dibromo-2-aryl-1-alkene II and azides via cyclization in the presence of catalyst and ligand. The azide is sodium azide, silver azide, or lead azide. The catalyst is selected from CuI, copper acetate, copper sulfate, or ferric chloride. The ligand is chosen from ascorbate salt, L-proline, N,N-di-Me ethylenediamine, or cysteine. The obtained compound can be used in synthesis and modification of medicine. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).SDS of cas: 5301-96-2
The Article related to aryltriazole preparation dibromoarylalkene azide cyclization, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.SDS of cas: 5301-96-2
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics