Synthesis, structure, and fungicidal activity of triorganotin (4H-1,2,4-triazol-4-yl)benzoates was written by Li, Fang-Lin;Dai, Bin;Song, Hai-Bin;Mi, Na;Tang, Liang-Fu. And the article was included in Heteroatom Chemistry in 2010.Application of 157069-48-2 This article mentions the following:
A series of triorganotin (4H-1,2,4-triazol-4-yl)benzoates have been synthesized by the reaction of 4-(4H-1,2,4-triazol-4-yl)benzoic acid and 3-(4H-1,2,4-triazol-4-yl)benzoic acid with (R3Sn)2O (R = Et, n-Bu and Ph) or R’3SnOH (R’ = p-tolyl and cyclohexyl). The mol. structure of tri(p-tolyl)tin 3-(4H-1,2,4-triazol-4-yl)benzoate determined by x-ray crystallog. displays that the tin atom adopts a five-coordinate distorted trigonal bipyramidal geometry with the carboxyl oxygen atom and the nitrogen atom on 1-position of triazole ring occupying the apical position. Moreover, this complex forms a polymeric chain by the intermol. Sn-N interactions. All these complexes show good antifungal activities in vitro against Alternaria solani, Cercospora arachidicola, Gibberella zeae, Physalospora piricola, and Botrytis cinerea. © 2010 Wiley Periodicals, Inc. Heteroatom Chem 20:411-417, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20566. In the experiment, the researchers used many compounds, for example, 4-(4H-1,2,4-Triazol-4-yl)benzoic acid (cas: 157069-48-2Application of 157069-48-2).
4-(4H-1,2,4-Triazol-4-yl)benzoic acid (cas: 157069-48-2) belongs to triazole derivatives. Triazoles consist of a five-membered ring containing three nitrogen atoms and are biologically active, especially as antifungal, antimicrobial and enzyme inhibitors. Both the triazoles and their derivatives have significant biological properties including antimicrobial, antiviral, antitubercular, anticancer, anticonvulsant, analgesic, antioxidant, anti-inflammatory, and antidepressant activities.Application of 157069-48-2
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics