《Gold catalyzed cascade reaction of 2-Alkynyl arylazides with 1,2,3-Triazoles to provide N1- and N2-Indol-3-yl 1,2,3-Triazole derivatives》 was written by Li, Tao; Chen, Bai-Ling; Zhu, Li-Li; Chen, Zili. Electric Literature of C2H3N3 And the article was included in Tetrahedron Letters in 2020. The article conveys some information:
A new method was developed to prepare N1 and N2-indol-3-yl 1,2,3-trizole products through gold catalyzed cascade reaction of o-alkynyl arylazides with 1,2,3-triazoles, in which, the in-situ generated α-imino gold carbene intermediate was intercepted by various types of triazole compounds N1-selective nucleophilic attack was favored to give moderate to high N1/N2 selectivity. In addition, indol-3-yl pyrazole compounds were also prepared by using the similar method. In the experiment, the researchers used many compounds, for example, 1H-1,2,3-Triazole(cas: 288-36-8Electric Literature of C2H3N3)
1H-1,2,3-Triazole(cas: 288-36-8) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties Electric Literature of C2H3N3
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics