Formula: C10H7F2N3O. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone, is researched, Molecular C10H7F2N3O, CAS is 86404-63-9, about Studies on synthesis, structure and biological activities of novel triazole compounds containing thioamide. Author is Xu, Liang-Zhong; Li, Wei-Hua; Li, Kai; Qin, Yong-Qi; Li, Chun-Li; Hou, Bao-Rong.
Four novel triazole compounds containing thioamide group were designed and synthesized by using triazole, Ph isothiocyanate and aryl Et ketones as starting materials. The desired intermediates were thus derivatives of α-(1H-1,2,4-triazol-1-yl)methyl ketones. Their structures were confirmed by elemental anal., 1H NMR, IR and MS spectra. The crystal structure of 1-[1-[(anilino)thiocarbonyl]-1-(4-fluorobenzoyl)methyl]-1,2,4-triazole [also, i.e., α-(fluorobenzoyl)-N-phenyl-1,2,4-triazole-1-ethanethioamide] has been determined by X-ray diffraction anal. The preliminary bioassays have shown that the title compounds exhibit certain antifungal activity.
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Reference:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics