On November 7, 2014, Liu, Zhenquan; Zhu, Daqian; Luo, Bingling; Zhang, Naiyuan; Liu, Qi; Hu, Yumin; Pi, Rongbiao; Huang, Peng; Wen, Shijun published an article.Category: triazoles The title of the article was Mild Cu(I)-Catalyzed Cascade Reaction of Cyclic Diaryliodoniums, Sodium Azide, and Alkynes: Efficient Synthesis of Triazolophenanthridines. And the article contained the following:
Linear iodoniums are widely used as arylating reagents. However, cyclic diaryl iodoniums are ignored despite their potential to initiate dual arylations, atom and step economically. In our current work, a three-component cascade reaction of cyclic diaryliodoniums, sodium azide, and alkynes has been successfully achieved under mild conditions, catalyzed by cheap copper species. The regioselectivity associated with unsym. iodoniums was enhanced by installing two methyls ortho and para to the IIII center. The reaction enables a rapid access to a variety of complex mols., triazolophenanthridine derivatives I [R1 = H, OMe, Me, etc.; R2 = H, OMe, Me, etc.; R3 = ph, 4-Me-ph, 4-F-ph, etc.]. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Category: triazoles
The Article related to cyclic diaryliodonium sodium azide alkyne, tandem azidation azide alkyne cycloaddition ullmann coupling copper catalyst, triazolophenanthridine preparation, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Category: triazoles
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics