Loubidi, Mohammed’s team published research in Tetrahedron Letters in 2018-03-14 | CAS: 24415-66-5

Tetrahedron Letters published new progress about Arylation. 24415-66-5 belongs to class triazoles, name is 7-Chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine, and the molecular formula is C6H5ClN4, Application of 7-Chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine.

Loubidi, Mohammed published the artcilePd-catalyzed Suzuki/Sonogashira cross-coupling reaction and the direct sp3 arylation of 7-chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine, Application of 7-Chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine, the main research area is methyltriazolopyrimidine chloro preparation aryl alkyne palladium catalyst Sonogashira coupling; arylalkynyl methyltriazolopyrimidine preparation; chloro methyltriazolopyrimidine preparation arylboronic acid palladium catalyst Suzuki coupling; aryl methyltriazolopyrimidine preparation bromobenzene palladium catalyst arylation; benzyl aryl methyltriazolopyrimidine preparation.

A rapid and efficient method was reported for the synthesis of the [1,2,4]triazolo[1,5-a]pyrimidine motif. Palladium catalyzed Suzuki and Sonogashira cross coupling reactions on 7-chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine were performed. The direct sp3 arylation of compounds resulting from the Suzuki reaction was then carried out.

Tetrahedron Letters published new progress about Arylation. 24415-66-5 belongs to class triazoles, name is 7-Chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine, and the molecular formula is C6H5ClN4, Application of 7-Chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine.

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics