Lu, Qixing; Wang, Tao; Wu, Qian; Cheng, Lijing; Luo, Han; Liu, Lei; Chu, Guobiao; Wang, Lufeng; Li, Baosheng published an article in 2022, the title of the article was C-H heteroarylation of aromatics via catalyst free SN2′ coupling cycloaromatization.Product Details of 5301-96-2 And the article contains the following content:
The construction of a carbon-carbon bond is the most fundamental aspect of synthetic chem. In this study, authors developed a catalyst-free SN2′ reaction of β-OTf-substituted enamides with aromatics to obtain aryl-substituted aza-1,4-dicarbonyl compounds that can be in situ transformed into aryl-imidazole, aryl-thiazole, and aryl-oxazole in one-pot operation, thus achieving C-H heteroarylation of aromatics This simple, efficient, clean and scalable strategy, which provides difficult-to-realize biaryl products, is compatible with various aromatics having varying complexities. This method can be used for the late-stage modification of various com. pharmaceuticals or functional materials and offers an orthogonal approach for constructing biaryl compounds The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Product Details of 5301-96-2
The Article related to aromatic compound heteroarylation coupling cycloaromatization, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amides, Amidines, Imidic Esters, Hydrazides, and Hydrazonic Esters and other aspects.Product Details of 5301-96-2
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics