《Organophotoredox-Catalyzed Direct C-H Amination of 2H-Indazoles with Amines》 was published in Organic Letters in 2020. These research results belong to Neogi, Sukanya; Ghosh, Asim Kumar; Majhi, Koushik; Samanta, Sadhanendu; Kibriya, Golam; Hajra, Alakananda. Application In Synthesis of 1H-1,2,3-Triazole The article mentions the following:
A general and practical method for the direct C-H amination of 2H-indazoles with a series of amines including aliphatic primary amines, secondary amines, azoles and sulfoximines via organophotoredox-catalyzed oxidative coupling to gave aryl(amine/imino)indazols I [R1 = 4-Me, 3-OMe, 4-i-Pr, etc.; R2 = H, 5-F, 5-Cl, 5-OMe; R3 = NH2, pyrazol-1-yl, 1-piperidyl, etc.] was disclosed at room temperature under ambient air conditions. Addnl., this protocol was used for free aminated 2H-indazole I [R1 = Me; R2 = H, 5-Cl; R3 = NH2] synthesis. A mechanistic study revealed that a single electron transfer (SET) pathway might be involved in this reaction.1H-1,2,3-Triazole(cas: 288-36-8Application In Synthesis of 1H-1,2,3-Triazole) was used in this study.
1H-1,2,3-Triazole(cas: 288-36-8) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties Application In Synthesis of 1H-1,2,3-Triazole
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics