New discoveries in chemical research and development in 2021. The dynamic chemical diversity of the numerous elements, ions and molecules that constitute the basis of life provides wide challenges and opportunities for research. 13423-60-4, name is 1-Phenyl-1H-1,2,4-triazole belongs to triazoles compound, it is a common compound, a new synthetic route is introduced below. Computed Properties of C8H7N3
EXAMPLE 109 1-phenyl-4-(prop-1-yl)triazolium bromide 0.300 g (0.002 mol) 1-phenyltriazole 1 and 0.188 ml (0.254 g, 0.002 mol) 1-bromopropane 2 were dissolved in a pressure tube in 5 ml THF. The reaction mixture was stirred for 1 h at 50 C.; however, because no precipitate formed, the temperature was raised first to 80 (2 h) and then to 110 C. After 21 h at 110 C. the reaction mixture was cooled down. A DC check still indicated considerable amounts of the educt 1, so that additional 0.376 ml (0.508 g, 0.004 mol) of the educt 2 was added and stirring was continued for 24 h at 110 C. Subsequently, the reaction mixture was cooled down to room temperature and the same volume petroleum ether was added. The precipitated solid is filtered off, washed with petroleum ether and dried in HV. M 268.16 Yield: 0.0374 g (7%) 1H-NMR DM-102.w (300 MHz/DMSO): (ppm)=0.98 (t, 3H, 9-H); 3.95 (q, 2H, 8-H); 4.31 (t, 2H, 7-H); 7.70 (m, 3H, 5/5’/6H); 7.96 (d, 2H, 4/4′-H); 9.51 (s, 1H, 1-H); 11.00 (s, 1H, 2-H) 13C-NMR DM-102 (74.475 MHz/DMSO):
If you are hungry for even more, make sure to check my other article about 13423-60-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; TECHNISCHE UNIVERSITAET DRESDEN; US2011/105761; (2011); A1;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics