41253-21-8, Adding some certain compound to certain chemical reactions, such as: 41253-21-8, name is Sodium 1,2,4-triazol-1-ide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 41253-21-8.
At room temperature, a four-necked bottle was charged with 120 g of acetonitrile, 1,2,4-triazole sodium salt (18.20 g, 0.2 mol), 2,4′-dichloroacetophenone (37.80 g, 0.2 mol) , heating to 80~85 C, heat preservation reaction 1-2h, the reaction is completed, the solvent is evaporated to dryness under reduced pressure, 50g of water is added, extracted with 150g of dichloromethane, washed with water, the solvent is dried, to obtain a white solid qualitative content of 98% The weight yield is 96%.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 41253-21-8.
Reference:
Patent; Huai’an Guorui Chemical Co., Ltd.; Wu Yaojun; Zhang Pu; Zhao Wei; Jin Yucun; Wang Fengyun; Chen Mingguang; Mao Gengsheng; (6 pag.)CN109535091; (2019); A;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics