Ni, Qijian; Song, Xiaoxiao; Xiong, Jiawen; Raabe, Gerhard; Enders, Dieter published an article in 2015, the title of the article was Regio- and stereoselective synthesis of benzothiazolo-pyrimidinones via an NHC-catalyzed Mannich/lactamization domino reaction.Electric Literature of 1469801-67-9 And the article contains the following content:
An NHC-catalyzed regio- and stereoselective Mannich/lactamization domino reaction of N-(benzothiazolyl)imines with α-chloroaldehydes has been developed. This new protocol provides a facile approach for the asym. synthesis of benzothiazolo-pyrimidinones and a pyrrolo[1,2-a]indolone in moderate to good yields (34-78%) and excellent stereoselectivities (87-99% ee, up to >20 : 1 d.r.). The experimental process involved the reaction of (R)-5-Benzyl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate(cas: 1469801-67-9).Electric Literature of 1469801-67-9
The Article related to regioselective stereoselective benzothiazolopyrimidinone preparation tandem reaction, nitrogen heterocyclic carbene catalyzed mannich lactamization domino reaction, domino reaction benzothiazolylimine alpha chloroaldehyde benzothiazolopyrimidinone pyrroloindolone preparation and other aspects.Electric Literature of 1469801-67-9
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics