On July 15, 2010, Oh, Sangtae; Shin, Woon-Seob; Ham, Jungyeob; Lee, Seokjoon published an article.HPLC of Formula: 5301-96-2 The title of the article was Acid-catalyzed synthesis of 10-substituted triazolyl artemisinins and their growth inhibitory activity against various cancer cells. And the article contained the following:
A diastereomeric and regioisomeric library of 10-triazolylartemisinins with potent growth-inhibitory activities against various cancer cell lines was established. These compounds were synthesized by the reaction with dihydroartemisinin and various triazoles in CH2Cl2 using BF3.OEt2 catalyst. Most of the compounds exhibited a strong potency in the submicromolar range, and, in particular, 3 compounds, having a (pentylphenyl)triazole moiety, proved to be promising candidates for preclin. trials. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).HPLC of Formula: 5301-96-2
The Article related to triazole artemisinin preparation anticancer, Terpenes and Terpenoids: Sesquiterpenes (C15), Including Ionones and other aspects.HPLC of Formula: 5301-96-2
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics