Okabe, Takayuki published the artcileSyntheses of triazolopyrimidine derivatives from amitrole and their biological activity, Quality Control of 24415-66-5, the main research area is triazolopyrimidine synthesis amitrole fungicide; herbicide triazolopyrimidine synthesis amitrole.
Amitrole (3-amino-1,2,4-triazole) (I) [61-82-5] was condensed with active methylene ketones such as Et cyanoacetate, acetylacetone, ethyl acetoacetate to give the corresponding 7-amino-5-hydroxy-s-triazolo[1,5-a]pyrimidine [35186-69-7], 5,7-dimethyl-s-triazolo[1,5-a]pyrimidine [7681-99-4], and 7-hydroxy-5-methyl-s-triazolo[1,5-a]pyrimidine (II) [2503-56-2]; from II some 5-methyl-7-substituted-s-triazolopyrimidines were synthesized and tested for herbicidal and fungicidal activity. 7-Chloro-5-methyl-s-triazolo[1,5-a]pyrimidine (III) [24415-66-5] synthesized from II plus POCl3, as well as 5-methyl-7-thiocyano-s-triazolo[1,5-a]pyrimidine (IV) [35186-71-1] prepared from III plus NH4SCN actively inhibited spore germination of Ophiobolus miyabeanus. IV showed antibiotic effects on Bacillus subtilis, Pellicularia filamentosa, [Rhizoctonia solani], and Phytophthora infestans and was herbicidally active on Atriplex gmelini, but showed no growth regulatory activity on rice.
Gakugei Zasshi – Kyushu Daigaku Nogakubu published new progress about Fungicides. 24415-66-5 belongs to class triazoles, name is 7-Chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine, and the molecular formula is C6H5ClN4, Quality Control of 24415-66-5.
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics