Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 13423-60-4, name is 1-Phenyl-1H-1,2,4-triazole, A new synthetic method of this compound is introduced below., Safety of 1-Phenyl-1H-1,2,4-triazole
A mixture of 1-phenyl-H-1,2,4-triazole 24 (364.3 mg, 2.51 mmol) and 2-fluoroethyl triflate (492.7 mg, 2.5 mmol) in toluene (2.5 ml) was heated at 130 C for 48 h. The solvent was evaporated and ther esidue titruated with Et2O (10 ml) to give the product as a white solid (803 mg, 94%).
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Paul, Susann; Schweizer, W. Bernd; Rugg, Graham; Senn, Hans Martin; Gilmour, Ryan; Tetrahedron; vol. 69; 27-28; (2013); p. 5647 – 5659;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics