Some common heterocyclic compound, 202931-88-2, name is 1-Methyl-1H-1,2,3-triazole-5-carbaldehyde, molecular formula is C4H5N3O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Product Details of 202931-88-2
[00377] (¡ê’)-3-(l-methyl-lH-l,2,3-triazol-5-yl)-l-(thiazol-2-yl)prop-2-en-l-one was prepared from l-(thiazol-2-yl)-2-(triphenyl- 5-phosphanylidene)ethan-l-one and 1-methyl- lH-l,2,3-triazole-5-carbaldehyde via Wittig reaction using synthetic procedures described for the preparation of the analog SW209415. ESI-MS (m/z): 221.1 [M+H]+.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 202931-88-2, its application will become more common.
Reference:
Patent; CASE WESTERN RESERVE UNIVERSITY; BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM; MARKOWITZ, Sanford D.; READY, Joseph; ZHANG, Yongyou; ANTCZAK, Monika; WILLSON, James K.V.; POSNER, Bruce A.; GREENLEE, William; (254 pag.)WO2016/168472; (2016); A1;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics