Some common heterocyclic compound, 13423-60-4, name is 1-Phenyl-1H-1,2,4-triazole, molecular formula is C8H7N3, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Safety of 1-Phenyl-1H-1,2,4-triazole
, mixing 100 mmol of sodium borohydride and 150 mmol of ammonium carbonate into 100 mmol of anhydrous dioxane, and adding 40 mmol of 1-phenyl -1, 2, 4-triazole, reacting at 70 DEG c for 12 hours under the protection of nitrogen, and filtering the crude product, and carrying out rotary evaporation to obtain a white solid product (a compound shown as a formula i/g) 7.81 g
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 13423-60-4, its application will become more common.
Reference:
Patent; Nanjing Tech University; Guan Guofeng; He Yuting; Ding Jing; Li Xue; Wan Hui; (9 pag.)CN108484654; (2018); A;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics