7170-01-6, Adding some certain compound to certain chemical reactions, such as: 7170-01-6, name is 3-Methyl-1H-1,2,4-triazole, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 7170-01-6.
Intermediate 1075-(3-Methyl-[i ,2,4ltriazol-i -yl)-ryrazine-2-carboxylic acid: A mixture of methyl 5-chloropyrazine-2-carboxylate (0.75 g), K2003 (1 .8 g) and 3- methyl-i H-i ,2,4-triazole(i .2 g) in N,N-dimethylformamide (6 mL) is heated to 100C overnight. Analysis of the crude mixture by LCMS shows saponified product. The product is acidified with 1 N hydrochloric acid and the precipitate is filtered andwashed with water and diethyl ether to afford the title compound. LC (method 20): tR = 1 .21 mm; Mass spectrum (APCI): m/z = 206 [M+H]
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 7170-01-6.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; NEUROCRINE BIOSCIENCES, INC.; NOSSE, Bernd; ECKHARDT, Matthias; HIMMELSBACH, Frank; LANGKOPF, Elke; ASHWEEK, Neil J.; HARRIOTT, Nicole; WO2014/19967; (2014); A1;,
1,2,3-Triazole – Wikipedia,
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