In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 288-88-0, name is 1H-1,2,4-Triazole belongs to triazoles compound, it is a common compound, a new synthetic route is introduced below. Product Details of 288-88-0
General procedure: 1 mmol of the compound of the formula II-1 and 2 mmol of the compound of the formula III are sequentially added to the reaction.0.5mmol% catalyst CS Cu2O,3mmol potassium phosphate and 0.5ml N,N-dimethylformamide solution, heated to 110 C to stir the reaction,After the TLC reaction was completed, the reaction was quenched with water and filtered for ethyl acetate.Washed with saturated brine, dried and concentrated.The product was obtained by silica gel column chromatography.
The synthetic route of 288-88-0 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Yancheng Jin Ming Pharmaceutical Co., Ltd.; Yancheng Normal College; Qian Cunwei; Feng Xuexin; Yang Zijian; Hu Chaojun; Qiu Yue; Wang Qingdong; Yang Jinming; (13 pag.)CN109608401; (2019); A;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics