7343-34-2, Adding a certain compound to certain chemical reactions, such as: 7343-34-2, name is 3,5-Dimethyl-4H-1,2,4-triazole, belongs to Triazoles compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 7343-34-2.
General procedure: A mixture of 1 g of 4-chloromethyl-1-(4-chloro-phenyl)-1H-[1,2,3]triazole, 0.5 g of 3,5- dimethyl-1H-[1,2,4]triazole and 1 g of potassium carbonate in 20 ml of DMF were stirred for 2 days. After filtration and evaporation of the solvent the crude product was purified by flash chromatography to form 0.6 g of the title compound (M+H+ 289.7, melting range 153-156 ¡ãC).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3,5-Dimethyl-4H-1,2,4-triazole, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; JANSSEN PHARMACEUTICALS, INC.; SCHINDLER, Rudolf; LANKAU, Hans-Joachim; HOeFGEN, Norbert; EGERLAND, Ute; LANGEN, Barbara; DOST, Rita; WARD, Simon; (89 pag.)WO2016/25917; (2016); A1;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics