Adding a certain compound to certain chemical reactions, such as: 81606-79-3, name is 2-(1,2,4-Triazol-1-yl)acetonitrile, belongs to Triazoles compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 81606-79-3, Computed Properties of C4H4N4
STR210 108 g (1 mole) of 1,2,4-triazol-1-yl-acetonitrile and 160 g (1.35 moles) of N,N-dimethylformamide dimethyl acetal are heated under reflux for 4 hours; the methanol formed is distilled off until the internal temperature has risen to 120 C.; the resulting residue is dissolved in 400 ml of ethanol, and 400 ml of a 20% strength ethanolic hydrogen chloride solution are added. The crystalline precipitate is filtered off with suction, rinsed with a little ethanol and dried on clay. 163 g (82% of theory) of 3-dimethylamino-2-(1,2,4-triazol-1-yl)-acrylonitrile hydrochloride of melting point 200-204 C. are obtained.
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Reference:
Patent; Bayer Aktiengesellschaft; US4614534; (1986); A;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics