In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 956317-36-5, name is 5-Methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid belongs to Triazoles compound, it is a common compound, a new synthetic route is introduced below. SDS of cas: 956317-36-5
General procedure 9Ar2-COOH (1 eq; prepared according to WO 2008147518 for compounds 49-51 ), HOBT (1 eq) and EDCI. HCI (1.5eq) dissolved in dichloromethane (5ml/mmol) were stirred at 25 C for 0.5-2hours, then intermediates 67-68 dissolved in dichloromethane were added. After 18 hours the mixture was poured in an aqueous saturated solution of NaHCO3 and extracted with dichloromethane. The crude was purified by silica gel column chromatography (DCM to DCIWMeOH = 9/1 )
The synthetic route of 956317-36-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; ROTTAPHARM S.P.A.; STASI, Luigi, Piero; ROVATI, Lucio; WO2011/6960; (2011); A1;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics