Squitieri, Richard A.; Fitzpatrick, Keegan P.; Jaworski, Ashley A.; Scheidt, Karl A. published an article in 2019, the title of the article was Synthesis and Evaluation of Azolium-Based Halogen-Bond Donors.Application In Synthesis of (R)-5-Benzyl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate And the article contains the following content:
A method for the synthesis of iodinated imidazolium and triazolium N-heterocyclic halogen-bond-donor catalysts was developed. This approach was applied to the synthesis of a variety of 1,2,4-triazolium salts to prepare a series of novel chiral halogen-bond-donor catalysts. The counterions of the iodinated triazoliums were readily exchanged with chiral and achiral non-coordinating counterions to produce unique scaffolds. Their ability to promote/catalyze a conjugate addition reaction with indole was investigated. Through these initial studies, a set of general guidelines and considerations for the application of these halogen-bond donors in organocatalysis was established. The experimental process involved the reaction of (R)-5-Benzyl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate(cas: 1469801-67-9).Application In Synthesis of (R)-5-Benzyl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate
The Article related to azolium salt catalyst preparation crystal structure, indole phenylbutenone azolium salt catalyst conjugate addition reaction, lewis bases, azolium, catalysis, conjugate addition, halogen bonding and other aspects.Application In Synthesis of (R)-5-Benzyl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics