Sun, Qingyan published the artcileSynthesis and antifungal activity of triazole derivatives, SDS of cas: 86386-77-8, the publication is Zhongguo Yaowu Huaxue Zazhi (2004), 14(1), 14-18, database is CAplus.
The effect of the triazole derivatives from introducing a side chain containing nitrogen on the antifungal activity was studied. Twenty-two title compounds were synthesized and confirmed by elementary anal., 1H-NMR and IR spectra. MIC80 of all the title compounds were determined using the RPM1640 test medium. The results of the preliminary antifungal test showed that all the title compounds exhibited potent antifungal activities. One compound showed equal or more potent activities when compared with ketoconazole and was markedly superior to fluconazole. Proper lipid/water distribution coefficient might be important to the antifungal activities of the title compounds in vitro.
Zhongguo Yaowu Huaxue Zazhi published new progress about 86386-77-8. 86386-77-8 belongs to triazoles, auxiliary class Epoxides,Triazole,Fluoride,Salt,Sulfonic acid,Benzene, name is 1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate, and the molecular formula is C4H4N2O2, SDS of cas: 86386-77-8.
Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics