Application of 7411-23-6, New discoveries in chemical research and development in 2021. We’ll be discussing some of the latest developments in chemical about CAS: 7411-23-6, name is 3,5-Dibromo-1H-1,2,4-triazole, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
SEM-Cl (808.41 mg, 4.85 mmol, 858.18 mL, 1 eq) was added to a dichloromethane solution (10 mL) of acompound WX073-1 (1.1g, 4.85mmol, 1 eq) and triethylamine (727.00 mg, 7.18mmol, 1 mL, 1.48 eq), and the resultingmixture was reacted 25C for 1 hour. The reaction solution was spin-dried to obtain the target compound WX073-2. ESIm/z: [M-TMS+O]-=300.1.
I am very proud of our efforts over the past few months and hope to 3,5-Dibromo-1H-1,2,4-triazole help many people in the next few years.
Reference:
Patent; Shandong Danhong Pharmaceutical Co., Ltd.; LUO, Zhi; LI, Xiaolin; YANG, Yaxun; YANG, Lele; LI, Peng; HE, Haiying; LI, Jian; CHEN, Shuhui; (155 pag.)EP3626699; (2020); A1;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics