Adding a certain compound to certain chemical reactions, such as: 584-13-4, name is 4H-1,2,4-Triazol-4-amine, belongs to Triazoles compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 584-13-4, 584-13-4
12.78 grams of sodium hypochlorite solution (36mM available chlorine) was dissolved inthe solution formed by mixing 5 mL glacial acetic acid with 30 mL of deionized water and the solution was cooled to 7 C. To this was added 1.5 g (18 mM) 4-amino-1,2,4-triazole dissolved in 15 mL deionized water. The solution was stirred at 7 C for 4 h followed by standing the final solution two days at room temperature. Yellow and oblong crystal of atrz (Supplemental data, figure S1) was obtained in 75% yield (scheme 1). This is very good for the synthesis of atrz, because the separation of the product, we know, always is the most difficult step during the whole synthetic experiment. In addition, sodium chloride, totally environment friendly, will only be left after atrz is separated from the final solution. Caution: The light, which makes sodium hypochlorite turn into sodium chloride and oxygen, must be obstructed during the whole reaction. Temperature is also very important to the yield of atrz because sodium hypochlorite is very unstable at high temperature (>25 C).Anal. Calcd for C4N8H4: C, 29.24; N, 68.32; H, 2.44. Found: C, 28.93; N, 68.36; H, 2.49. IR(cm-1) = 3111(s), 1489(s), 1368(s), 1315(m), 1176(s).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4H-1,2,4-Triazol-4-amine, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Li; Wu; Qiu; Zhang; Yang; Journal of Coordination Chemistry; vol. 67; 11; (2014); p. 2016 – 2027;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics