Computed Properties of C2H4N4. In 2020.0 J HETEROCYCLIC CHEM published article about THIAZOLE DERIVATIVES; MOLECULAR DESIGN; ANTITUMOR; AGENTS in [Abed, Nader A.; Hammouda, Mohamed M.; Ismail, Mohamed A.; Abdel-Latif, Ehab] Mansoura Univ, Fac Sci, Chem Dept, Mansoura 35516, Egypt in 2020.0, Cited 37.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.
The chemical performance of 5-bromo-2-(bromoacetyl)-thiophene (1) was tested toward the reaction with numerous bi-nucleophilic reagents (namely; 2-aminobenzothiazoles, 2-aminothiazole, 2-aminotetrazole, 2-aminotriazole, 2-aminopyridines, 2-aminobenzimidazole ando-phenylenediamine). Therefore, a series of bridged nitrogen heterocycles bearing thiophene moiety3,5,7,9,11,13and15, respectively was synthesized. In addition, the reaction of 5-bromo-2-(bromoacetyl)-thiophene with the thiocarbamoyl compounds17,19and/or24afforded the corresponding thienyl-thiazoles18or dithien-2-yl ketones20and25, based on the reaction conditions. Treatment of1with 2-mercapto-4,6-dimethylnicotinonitrile was achieved to obtain the target dithien-2-yl ketone28. The new synthesized scaffolds were examined for their antioxidant activity by means of ABTS antioxidant assay. The thienyl-thiazole scaffold18cand 2-((2-[thiophen-2-yl]-2-oxoethyl)thio)nicotinonitrile derivative27displayed a reasonable radical scavenging activity.
Computed Properties of C2H4N4. Welcome to talk about 61-82-5, If you have any questions, you can contact Abed, NA; Hammouda, MM; Ismail, MA; Abdel-Latif, E or send Email.
Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics