Synthesis of acyl- and vinyl-substituted 1,2,3-triazoles was written by Vereshchagin, L. I.;Tikhonova, L. G.;Maksikova, A. V.;Gavrilov, L. D.;Gareev, G. A.. And the article was included in Zhurnal Organicheskoi Khimii in 1979.Recommanded Product: 40594-98-7 This article mentions the following:
Acyltriazoles I [R = Ph, Me, HO, p-MeOC6H4, Me2CH, 3,4-(MeO)2 C6H3, R1 = HOCMe2, CH2OH, CH2C(OH)Me2, Bz, Ph, H, CO2H, p-MeC6H4, p-MeOC6H4, R2 = H, CH2CH2Cl] were prepared in 52-91% yields by cyclization of RCOCCR1, prepared by oxidation of RC(OH)CCR1, with R2N3. Triazoles II (R = Ph, EtO, R1 = HOCMe2, Bz, Ph, H) were obtained in 30-59% yields by treatment of the corresponding RCOCCR1 with I (R = R1 = Ph, R2 = H). In the experiment, the researchers used many compounds, for example, Ethyl 1H-1,2,3-triazole-5-carboxylate (cas: 40594-98-7Recommanded Product: 40594-98-7).
Ethyl 1H-1,2,3-triazole-5-carboxylate (cas: 40594-98-7) belongs to triazole derivatives. Triazoles exhibit substantial isomerism, depending on the positioning of the nitrogen atoms within the ring. Both the triazoles and their derivatives have significant biological properties including antimicrobial, antiviral, antitubercular, anticancer, anticonvulsant, analgesic, antioxidant, anti-inflammatory, and antidepressant activities.Recommanded Product: 40594-98-7
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics