Oxidative Palladium Catalysis in SNAr Reactions Leading to Heteroaryl Ethers from Pyridotriazol-1-yloxy Heterocycles with Aryl Boronic Acids was written by Wacharasindhu, Sumrit;Bardhan, Sujata;Wan, Zhao-Kui;Tabei, Keiko;Mansour, Tarek S.. And the article was included in Journal of the American Chemical Society in 2009.SDS of cas: 156311-83-0 The following contents are mentioned in the article:
The palladium-catalyzed oxidative coupling of pyrido- and benzotriazol-1-yloxyquinazolines and -thienopyrimidines, e.g., I, with aryl boronic acids in the presence of Pd(PPh3)4 and Cs2CO3 under oxygen in DME containing 0.4-0.8% water for the preparation of heteroaryl ethers, e.g., II, is described. These transformations of triazol-1-yloxy reagents demonstrate excellent O-chemoselective control under mild conditions and good yields. Mechanistic studies based on 18O labeling indicate that phenols as intermediates in SNAr reactions with ethers are formed in oxidative and nonoxidative pathways. This study involved multiple reactions and reactants, such as ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0SDS of cas: 156311-83-0).
((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. Triazoles are important five-member nitrogen heterocycles involved in a wide range of industrial applications such as agrochemicals, corrosion inhibitors, dyes, optical brighteners, as well as biologically active agents. Triazoles are compounds with a vast spectrum of applications, varying from materials (polymers), agricultural chemicals, pharmaceuticals, photoactive chemicals and dyes.SDS of cas: 156311-83-0
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics