Wang, Shu-dong published the artcileSynthesis and antifungal activity of the novel triazole compounds, SDS of cas: 86386-77-8, the publication is Yaoxue Shijian Zazhi (2011), 29(6), 426-430, database is CAplus.
To design, synthesis and evaluate the antifungal active of the novel triazole compounds based on the structure of fluconazole, the big N,N-disubstituted group was introduced and a series of compounds were synthesized, all of them were confirmed by MS and 1H NMR, et al. Eighteen triazole compounds I(R = 2-F, 3-F, 4-F, 2-Cl, 3-Cl, 4-Cl, 2-Br, 3-Br, 2-Me, 3-Me, 4-Me, 2-NO2, 3-NO2, 4-NO2, 2-CN, 3-CN, 4-CN, H) were synthesized and the antifungal activity were also evaluated against the eight common pathogenic fungi. The big N,N-disubstituted group introduced to the side chain could affected the antifungal activity.
Yaoxue Shijian Zazhi published new progress about 86386-77-8. 86386-77-8 belongs to triazoles, auxiliary class Epoxides,Triazole,Fluoride,Salt,Sulfonic acid,Benzene, name is 1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate, and the molecular formula is C20H19NO4, SDS of cas: 86386-77-8.
Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics