What Kind of Chemistry Facts Are We Going to Learn About 1H-1,2,4-Triazol-5-amine

COA of Formula: C2H4N4. Welcome to talk about 61-82-5, If you have any questions, you can contact Sweidan, NI; El-Abadelah, MM; Nazer, MZ; Voelter, W or send Email.

Recently I am researching about THIENOPYRIDINONE ANTIBACTERIALS; BIOLOGICAL EVALUATION; PART; DERIVATIVES; ACIDS, Saw an article supported by the Deanship of Scientific Research at the University of Jordan, Amman-Jordan. COA of Formula: C2H4N4. Published in WALTER DE GRUYTER GMBH in BERLIN ,Authors: Sweidan, NI; El-Abadelah, MM; Nazer, MZ; Voelter, W. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

Interaction of methyl 3-ethoxy-2-(2,5-dichloro-3-thenoyl)acrylate (I) with 3-aminopyrazole and 3- amino-1,2,4-triazole generated the respective pyrazolo [1,5-alpha]pyrimidine (4) and triazolo[1,5-alpha]pyrimidine (7). The formation of 4 entails selective and consecutive displacement of the 3-ethoxy and methoxy (ester) anions in I by 3-NH2 and 1-NH of 3-aminopyrazole. On the other hand, the formation of 7 implies selective displacement of 3-ethoxy in I by the ring-NH followed by cyclocondensation involving the keto group in I and 3-NH2 of aminotriazole. This latter selective displacement sequence is also followed by 3-amino-5-hydroxypyrazole in its reaction with I. The structures of the new compounds are supported by microanalytical and spectral data.

COA of Formula: C2H4N4. Welcome to talk about 61-82-5, If you have any questions, you can contact Sweidan, NI; El-Abadelah, MM; Nazer, MZ; Voelter, W or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics