Fan, NJ; Tang, JJ; Li, YF; Bai, YB; Zhao, XM in [Fan, Ning-Juan; Li, Yuan-Feng] Northwest A&F Univ, Coll Life Sci, Yangling 712100, Shaanxi, Peoples R China; [Tang, Jiang-Jiang] Northwest A&F Univ, Sch Chem & Pharm, Shaanxi Key Lab Nat Prod & Chem Biol, Yangling 712100, Shaanxi, Peoples R China; [Bai, Yu-Bin; Zhao, Xiao-Min] Northwest A&F Univ, Coll Vet Med, Yangling 712100, Shaanxi, Peoples R China published SYNTHESIS OF STEROIDAL [1,2,4]TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR ANTIPROLIFERATIVE ACTIVITIES in 2019.0, Cited 19.0. SDS of cas: 61-82-5. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.
A facile strategy for the synthesis of steroidal [1,2,4]triazolo[1,5-a]pyrimidines 5a-g and 6a-g has been accomplished via a one-pot reaction of steroidal ketones, aromatic aldehydes and 3-amino-1,2,4-triazole in the presence of potassium tert-butoxide in refluxing tert-butanol. All the synthesized heterosteroids were evaluated for in vitro antiproliferative activity against human cancer cells by sulforhodamine B (SRB) assays. The preliminary results showed that compounds 6a and 6e possessed potent antiproliferative activities.
Welcome to talk about 61-82-5, If you have any questions, you can contact Fan, NJ; Tang, JJ; Li, YF; Bai, YB; Zhao, XM or send Email.. SDS of cas: 61-82-5
Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics