Chemical suppressors of mlo-mediated powdery mildew resistance was written by Wu, Hongpo;Kwaaitaal, Mark;Strugala, Roxana;Schaffrath, Ulrich;Bednarek, Pawel;Panstruga, Ralph. And the article was included in Bioscience Reports in 2017.Application In Synthesis of 1H-Benzo[d][1,2,3]triazol-1-amine This article mentions the following:
Loss-of-function of barley mildew locus o (Mlo) confers durable broad-spectrum penetration resistance to the barley powdery mildew pathogen, Blumeria graminis f. sp. hordei (Bgh). Given the importance of mlo mutants in agriculture, surprisingly few mol. components have been identified to be required for this type of resistance in barley. With the aim to identify novel cellular factors contributing to mlo-based resistance, we devised a pharmacol. inhibitor screen. Of the 41 rationally chosen compounds tested, five caused a partial suppression of mlo resistance in barley, indicated by increased levels of Bgh host cell entry. These chems. comprise brefeldin A (BFA), 2′,3′-dideoxyadenosine (DDA), 2-deoxy-
1H-Benzo[d][1,2,3]triazol-1-amine (cas: 1614-12-6) belongs to triazole derivatives. However, triazoles are also useful in bioorthogonal chemistry, because the large number of nitrogen atoms causes triazoles to react similar to azides. Triazole growth retardants such as uniconazole and paclobutrazol have been known to inhibit the biosynthesis of gibberellins by blocking kaurene oxidase, an P450 enzymeApplication In Synthesis of 1H-Benzo[d][1,2,3]triazol-1-amine
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics