Xu, Jun’s team published research in Zhongguo Yaowu Huaxue Zazhi in 8 | CAS: 86386-77-8

Zhongguo Yaowu Huaxue Zazhi published new progress about 86386-77-8. 86386-77-8 belongs to triazoles, auxiliary class Epoxides,Triazole,Fluoride,Salt,Sulfonic acid,Benzene, name is 1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate, and the molecular formula is C7H5Cl2NO, Related Products of triazoles.

Xu, Jun published the artcileSynthesis and antifungal activity of N-[3-(1H-1,2,4-triazol-1-yl)-2-(2,4-difluorophenyl)-2-hydroxypropyl]aminoacetic acid and its derivatives, Related Products of triazoles, the publication is Zhongguo Yaowu Huaxue Zazhi (1998), 8(3), 182-187, database is CAplus.

N-[3-(1H-1,2,4-Triazole-1-yl)-2-(2,4-difluorophenyl)-2-hydroxypropyl]aminoacetic acid and its 9 derivatives were designed and synthesized and evaluated for antifungal activities in vitro. The results of preliminary antifungal tests showed that some compounds exhibited potent activities against dermophytes, but lower activities against systematic pathogenic fungi except Cladosporium carrioni. The activities of compounds (5e) and (5h) were markedly superior to fluconazole, but less potent than those of ketoconazole in vitro.

Zhongguo Yaowu Huaxue Zazhi published new progress about 86386-77-8. 86386-77-8 belongs to triazoles, auxiliary class Epoxides,Triazole,Fluoride,Salt,Sulfonic acid,Benzene, name is 1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate, and the molecular formula is C7H5Cl2NO, Related Products of triazoles.

Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics