Yan, Yongzheng’s team published research in Archives of Pharmacal Research in 34 | CAS: 86386-77-8

Archives of Pharmacal Research published new progress about 86386-77-8. 86386-77-8 belongs to triazoles, auxiliary class Epoxides,Triazole,Fluoride,Salt,Sulfonic acid,Benzene, name is 1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate, and the molecular formula is C8H11NO, SDS of cas: 86386-77-8.

Yan, Yongzheng published the artcileSynthesis and antifungal activity of novel triazole derivatives, SDS of cas: 86386-77-8, the publication is Archives of Pharmacal Research (2011), 34(10), 1649-1656, database is CAplus and MEDLINE.

A series of novel azoles, which are analogs of fluconazole, were designed and synthesized as potential antifungal agents by the click reaction. The click reaction approach toward the synthesis of novel 1,2,3-triazolyl linked triazole antifungal derivatives was achieved by Cu(I)-catalyzed 1,3-dipolar cycloaddition of 2-(2,4-difluorophenyl)-3-propargylamino-1-(1,2,4-triazol-1-yl)-2-propanol with substituted benzyl bromides and sodium azide. In addition, the target compounds tested can increase antifungal activity.

Archives of Pharmacal Research published new progress about 86386-77-8. 86386-77-8 belongs to triazoles, auxiliary class Epoxides,Triazole,Fluoride,Salt,Sulfonic acid,Benzene, name is 1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate, and the molecular formula is C8H11NO, SDS of cas: 86386-77-8.

Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics