Yokoi, Masateru published the artcile< Catalase, activity of isoniazid-resistant tubercle bacilli>, Name: 6-Bromo-3H-[1,2,3]triazolo[4,5-b]pyridine, the main research area is .
Isonicotinic acid hydrazide-resistant strains of Mycobacterium tuberculosis var. hominis showed a decreased catalase activity. Addition of heroin and coenzyme A to the homogenate of the resistant strains failed to increase catalase activity. However, porphyrin synthesis from δ-aminolevulinic acid showed little or no difference from that of non-resistant strains. Incubation of the resistant strains with this acid, yeast extract, lysine, glycine, alanine, γ-aminobutyric, aspartic, and glutamic acids, proline, histidine, and phenylalanine markedly increased catalase activity. The potentiating effect of these reagents was inhibited by chloramphenicol, dihydrostreptomycin, and 8-azaguanine. Deficiency of the apoprotein may be responsible for the low catalase activity of resistant strains.
Osaka Daigaku Igaku Zasshi published new progress about Mycobacterium tuberculosis. 92276-38-5 belongs to class triazoles, and the molecular formula is C5H3BrN4, Name: 6-Bromo-3H-[1,2,3]triazolo[4,5-b]pyridine.
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics