Research speed reading in 2021. We’ll be discussing some of the latest developments in chemical about CAS: 1001401-62-2, name is 2-(2H-1,2,3-Triazol-2-yl)benzoic acid belongs to triazoles compound, it is a common compound, a new synthetic route is introduced below. Quality Control of 2-(2H-1,2,3-Triazol-2-yl)benzoic acid
j0814] To the title compound of step B (140 mg, 0.5 mmol) and intermediate A-i (113 g, 0.6 mmol) in DMF (4 mE) was added DIPEA (230 jt, 1.4 mmol) and HATU (155 g, 0.6 mmol). Upon completion of the reaction, purification was performed using Agilent prep method X to give the title compound (172 g, 74%). MS (ESI) mass calcd. for C2QH,8F3N70, 429.2; mlz found 430 [M+H]. 1H NMR (CDC13): 8.32 (s, 0.3H), 8.17 (s, 0.7H), 7.99-7.89 (m, i.5H), 7.88-7.77 (m, 1 .5H), 7.62-7.30 (m, 4H), 6.24-6.15 (m, 0.3H),4.86 (s, 0.7H), 4.76 (d, J=5.4 Hz, 0.3H), 4.45-4.23 (m, 1H),
In conclusion, we affirm that quantitative kinetic descriptions of catalytic behavior continue to serve as an indispensable tool to navigate research efforts intended to model. Read on for other articles about 1001401-62-2.
Reference:
Patent; Janssen Pharmaceutica NV; COATE, Heather R.; DVORAK, Curt A.; FITZGERALD, Anne E.; LEBOLD, Terry P.; PREVILLE, Cathy; SHIREMAN, Brock T.; (473 pag.)US2016/46640; (2016); A1;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics