Research speed reading in 2021. The dynamic chemical diversity of the numerous elements, ions and molecules that constitute the basis of life provides wide challenges and opportunities for research. 15988-11-1, name is 4-Phenyl-1,2,4-triazolidine-3,5-dione belongs to triazoles compound, it is a common compound, a new synthetic route is introduced below. Quality Control of 4-Phenyl-1,2,4-triazolidine-3,5-dione
General procedure: A mixture of malononitrile (1.0 mmol), aromatic aldehyde (1.0 mmol), 4-ar ylurazole (1.0 mmol), and nano-ZrO2(20 mol %) was heated at 100C for 30-40 min. After completion of the reaction as indicated by TLC, the reaction mixture was cooled to room temperature. The solid residue was dissolved in hot ethanol and centrifuged to separate the catalyst. By recrystallization from ethanol, pure products were obtained.
The catalyzed pathway has a lower Ea, but the net change in energy that results from the reaction is not affected by the presence of a catalyst. In my other articles, you can also check out more blogs about 15988-11-1
Reference:
Article; Anaraki-Ardakani, Hossein; Heidari-Rakati, Tayebe; Oriental Journal of Chemistry; vol. 32; 3; (2016); p. 1625 – 1629;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics