Yu, Shichong’s team published research in RSC Advances in 3 | CAS: 86386-77-8

RSC Advances published new progress about 86386-77-8. 86386-77-8 belongs to triazoles, auxiliary class Epoxides,Triazole,Fluoride,Salt,Sulfonic acid,Benzene, name is 1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate, and the molecular formula is C20H21ClN4O4, Product Details of C12H13F2N3O4S.

Yu, Shichong published the artcileMolecular docking, design, synthesis and antifungal activity study of novel triazole derivatives containing the 1,2,3-triazole group, Product Details of C12H13F2N3O4S, the publication is RSC Advances (2013), 3(32), 13486-13490, database is CAplus.

A series of 1-(1H-1,2,4-triazol-1-yl)-2-(2,4-difluorophenyl)-3-[N-propyl-N-((1-substituted-1H-1,2,3-triazol-4-yl)methyl)amino]-2-propanols which are analogs of fluconazole, have been designed and synthesized on the basis of computational docking experiments to the active site of the cytochrome P 450 14α-demethylase (CYP51). Their structures were characterized by 1H NMR, 13C NMR and HR ESI MS. The MIC80 values indicate that the target compounds, e.g., I, showed higher activities against nearly all the fungi tested to some extent except against A. fum. and T. rub. All of the target compounds exhibited higher activities against C. alb. SC5314 and C. alb. Y0109 than all of the six pos. controls.

RSC Advances published new progress about 86386-77-8. 86386-77-8 belongs to triazoles, auxiliary class Epoxides,Triazole,Fluoride,Salt,Sulfonic acid,Benzene, name is 1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate, and the molecular formula is C20H21ClN4O4, Product Details of C12H13F2N3O4S.

Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics