Catalytic asymmetric electrochemical α-arylation of cyclic β-ketocarbonyls with anodic benzyne intermediates was written by Zhang, Qinglin;Guo, Chang. And the article was included in Youji Huaxue in 2020.Quality Control of 1H-Benzo[d][1,2,3]triazol-1-amine This article mentions the following:
This achieved the use of electrochem. methods to generate highly active benzyne or cyclohexyne intermediates, cleverly combined cobalt acetate with benzyne or cyclohexyne intermediates, improved the stability of the phenylyne intermediates, and successfully combined with cyclic β-ketocarbonyl compound activated by the chiral primary amine catalyst developed by the research group, and realized the synthesis of various high enantioselective α-aryl and α-cyclohexenyl derivatives In the experiment, the researchers used many compounds, for example, 1H-Benzo[d][1,2,3]triazol-1-amine (cas: 1614-12-6Quality Control of 1H-Benzo[d][1,2,3]triazol-1-amine).
1H-Benzo[d][1,2,3]triazol-1-amine (cas: 1614-12-6) belongs to triazole derivatives. Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior pharmacological applications. Triazole growth retardants such as uniconazole and paclobutrazol have been known to inhibit the biosynthesis of gibberellins by blocking kaurene oxidase, an P450 enzymeQuality Control of 1H-Benzo[d][1,2,3]triazol-1-amine
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics