Zhang, Zhiqiang published the artcileSynthesis and antifungal activities of novel triazole derivatives with dithiocarbamates side chain, Formula: C12H13F2N3O4S, the publication is Yaoxue Fuwu Yu Yanjiu (2016), 16(2), 94-97, database is CAplus.
Objective: To synthesize a series of novel triazole derivatives with dithiocarbamates side chain and evaluate their antifungal activities. Methods: Nine target compounds were synthesized and their structure characterizations were conformed by 1H-NMR and MS spectra. The in vitro antifungal activities of all the compounds were evaluated against eight human pathogenic fungi. Results: Potent antifungal activities were exhibited in all the target compounds, some of which showed potent antifungal activity against Candida glabrata (sown in I and II as examples), which was superior to such control drugs as fluconazole. Conclusion: The target compounds with dithiocarbamates side chain have potent antifungal activity.
Yaoxue Fuwu Yu Yanjiu published new progress about 86386-77-8. 86386-77-8 belongs to triazoles, auxiliary class Epoxides,Triazole,Fluoride,Salt,Sulfonic acid,Benzene, name is 1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate, and the molecular formula is C20H17FO4S, Formula: C12H13F2N3O4S.
Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics